Addressing the challenges posed by RND systems involves a multi-faceted approach. This includes the development of new antibiotics that are not susceptible to efflux by RND pumps, the use of efflux pump inhibitors that can block the action of these systems, and the implementation of robust antibiotic stewardship programs to minimize the unnecessary use of antibiotics. Additionally, ongoing research is essential to better understand the structure and function of RND systems and to identify potential targets for new therapeutic interventions.
