Preventing the spread of MDR bacteria requires a multi-faceted approach: 1. Antibiotic Stewardship - Rational use of antibiotics to minimize unnecessary exposure and reduce selective pressure. 2. Infection Control Measures - Implementing hygiene practices, such as hand washing, sterilization of equipment, and isolation of infected patients. 3. Surveillance - Monitoring and tracking the spread of MDR bacteria to identify and contain outbreaks. 4. Public Education - Informing the public and healthcare professionals about the risks and prevention strategies for antibiotic resistance.