How Can Genetic Epidemiology Benefit from Neuroanatomical Knowledge?

Genetic epidemiology explores the role of genetic factors in disease distribution and prevalence. Neuroanatomical knowledge aids in identifying how genetic mutations affect specific brain regions. For instance, mutations in the amyloid precursor protein (APP) gene are linked to amyloid plaques in the brain, a hallmark of Alzheimer's disease. This understanding can drive genetic screening and early intervention strategies.