Quantification limits are usually determined through a combination of laboratory experiments and statistical analysis. Key methods include:
1. Analytical Sensitivity: Evaluating the smallest concentration that can be detected but not necessarily quantified. 2. Calibration Curves: Using known concentrations to create a curve that helps identify the limit of detection (LOD) and limit of quantification (LOQ). 3. Validation Studies: Conducting repeated tests to ensure reliability and consistency of the measurement process.
