The study of epigenetic markers involves various techniques. DNA methylation can be analyzed using methods like bisulfite sequencing and methylation-specific PCR. Histone modifications can be examined through chromatin immunoprecipitation (ChIP) followed by sequencing. Advances in next-generation sequencing technologies and bioinformatics tools have enabled high-throughput analysis of epigenetic modifications across the genome, facilitating large-scale epidemiological studies.
