candidate gene studies

How are Candidate Genes Selected?

Candidate genes are typically selected based on:
1. Biological Plausibility: Genes involved in disease-related pathways or biological processes.
2. Previous Research: Findings from previous genetic studies, such as genome-wide association studies (GWAS).
3. Positional Cloning: Genes located in chromosomal regions linked to the disease in linkage studies.
4. Animal Models: Genes identified through studies in animal models that mimic human diseases.

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