Several advanced technologies are employed in EWAS, including:
1. Bisulfite Sequencing: This method converts unmethylated cytosines to uracil, allowing for the precise mapping of methylation sites. 2. Microarrays: These are used for genome-wide methylation profiling and are cost-effective for large-scale studies. 3. Next-Generation Sequencing (NGS): NGS technologies offer high-resolution and comprehensive epigenomic data but are more expensive.
