Bastiaan T. Heijmans - Epidemiology

Author Information

Bastiaan T. Heijmans is affiliated with the Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands. His work spans various aspects of molecular epidemiology and biomedical data sciences, with a particular focus on the epigenetic and transcriptomic changes associated with various diseases and conditions.

Research Contributions

Bastiaan T. Heijmans has made significant contributions to the fields of epigenetics, genomics, and immunometabolism. His recent works include studies on the activation of T and NK cells as drivers of epigenetic clock progression, alterations in DNA methylation related to metabolic and inflammatory pathways in ALS, and the impact of fatty acids on T-cell function and atherosclerosis. He has also explored the persistent epigenetic signatures in identical twins and the inheritance of environmentally induced DNA methylation across generations. His work is pivotal in understanding the genetic and epigenetic underpinnings of various diseases, which could lead to new therapeutic strategies.

Aliases

Bastiaan T. Heijmans is also known by various aliases including Bas T Heijmans, B.t Heijmans, Bas Heijmans, B. T. Heijmans, and B T Heijmans.

Publication and Citation Metrics

Metric	Value
Total Citation Count	18,486
h-index	64
Paper Count	241

Publications:

Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression

DOI: 10.1186/s13059-021-02585-8

Year: 2022

Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS

DOI: 10.1126/scitranslmed.abj0264

Year: 2022

Fatty acid-induced transcriptomic and methylomic changes in T-cells are involved in immunometabolism

DOI: 10.1016/j.atherosclerosis.2021.06.323

Year: 2021

Respiratory distress syndrome and bronchopulmonary dysplasia after fetal growth restriction: Lessons from a natural experiment in identical twins

DOI: 10.1016/j.eclinm.2021.100725

Year: 2021

Identical twins carry a persistent epigenetic signature of early genome programming

DOI: 10.1038/s41467-021-25583-7

Year: 2021

Effects of fatty acids on T cell function: role in atherosclerosis

DOI: 10.1038/s41569-021-00582-9

Year: 2021

Omixer: multivariate and reproducible sample randomization to proactively counter batch effects in omics studies

DOI: 10.1093/bioinformatics/btab159

Year: 2021

Sex-dependent gene regulation of human atherosclerotic plaques by DNA methylation and transcriptome integration points to smooth muscle cell involvement in women

DOI: 10.1101/2021.01.28.428414

Year: 2021

Environmentally-induced DNA methylation is inherited across generations in an aquatic keystone species (Daphnia magna)

DOI: 10.1101/2021.12.05.471257

Year: 2021

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

DOI: 10.1038/s41588-021-00913-z

Year: 2021

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