Development Of Novel Inhibitors - Epidemiology

Relevant Publications

Research progress on the pathogenesis of psoriasis and its small molecule inhibitors.

Issue Release: 2025

Orthoallosteric EGFR-TKIs: A New Paradigm in NSCLC Treatment Strategy Targeting the C797S Mutation.

Issue Release: 2025

Exploring the druggability of the UEV domain of human TSG101 in search for broad-spectrum antivirals.

Issue Release: 2025

Discovery of a first-in-class protein degrader for the c-ros oncogene 1 (ROS1).

Issue Release: 2024

(5S)-5-Benzylswainsonines as potent and selective inhibitors of Golgi α-mannosidase II: synthesis, enzyme evaluation and molecular modelling.

Issue Release: 2024

Sodium-glucose cotransporter 2 inhibitors induce anti-inflammatory and anti-ferroptotic shift in epicardial adipose tissue of subjects with severe heart failure.

Issue Release: 2024

Derivatives of D(-) glutamine-based MMP-2 inhibitors as an effective remedy for the management of chronic myeloid leukemia-Part-I: Synthesis, biological screening and in silico binding interaction analysis.

Issue Release: 2024

A novel FAK-degrading PROTAC molecule exhibited both anti-tumor activities and efficient MDR reversal effects.

Issue Release: 2024

Unveiling the promise of pyrimidine-modified CDK inhibitors in cancer treatment.

Issue Release: 2024

NAMPT Overexpression Drives Cell Growth in Polycystic Liver Disease Through Mitochondrial Metabolism Regulation.

Issue Release: 2024

Lessons learned from the Eµ-TCL1 mouse model of CLL.

Issue Release: 2024

Reconstitution of the alternative pathway of the complement system enables rapid delineation of the mechanism of action of novel inhibitors.

Issue Release: 2024

Novel carbazole-oxadiazole derivatives as anti-α-glucosidase and anti-α-amylase agents: Design, synthesis, molecular docking, and biological evaluation.

Issue Release: 2024

Exploring novel dilazep derivatives as hENT1 inhibitors and potentially covalent molecular tools.

Issue Release: 2024

The CDK9 inhibitor enitociclib overcomes resistance to BTK inhibition and CAR-T therapy in mantle cell lymphoma.

Issue Release: 2024

Synthesis and anticancer properties of novel dolastatin 10 analogs featuring five-membered heterocyclic rings with a linkable group at the C-terminus.

Issue Release: 2024

Next generation antimitotic β-carboline derivatives modulate microtubule dynamics and downregulate NF-κB, ERK 1/2 and phospho HSP 27.

Issue Release: 2024

Unveiling potential inhibitors targeting the nucleocapsid protein of SARS-CoV-2: Structural insights into their binding sites.

Issue Release: 2024

Phage display identification of high-affinity ligands for human TSG101-UEV: A structural and thermodynamic study of PTAP recognition.

Issue Release: 2024

Diagnosis and management of resistant hypertension.

Issue Release: 2024

What Challenges Do Mobile Health Clinics Face?

What is Initial Fieldwork?

What Are the Ethical Considerations in Political Involvement in Epidemiology?

How Does Secondary Prevention Differ from Primary and Tertiary Prevention?

What Role Does Race and Ethnicity Play?

What are the Epidemiological Patterns of Diarrhea?

What are the Challenges in Risk Stratification?

How Has Global Collaboration Improved?

How Is Model Validation Conducted?

What are Transport Mechanisms in Epidemiology?

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