Brca1 Or Brca2 - Epidemiology

Relevant Publications

Spectrum and characteristics of germline PALB2 pathogenic variants in 1556 early-onset breast cancer patients in China.

Issue Release: 2024

Genomic instability in non-breast/ovarian malignancies of individuals with germline pathogenic variants in BRCA1/2.

Issue Release: 2024

Schlafen 11 further sensitizes BRCA-deficient cells to PARP inhibitors through single-strand DNA gap accumulation behind replication forks.

Issue Release: 2024

BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance.

Issue Release: 2024

Abiraterone, Olaparib, or Abiraterone + Olaparib in First-line Metastatic Castration-Resistant Prostate Cancer with DNA Repair Defects (BRCAAway).

Issue Release: 2024

Phenotypes of carriers of two mutated alleles in major cancer susceptibility genes.

Issue Release: 2024

The dynamics and regulation of PARP1 and PARP2 in response to DNA damage and during replication.

Issue Release: 2024

Synergistic cytotoxicity of histone deacetylase and poly-ADP ribose polymerase inhibitors and decitabine in pancreatic cancer cells: Implications for novel therapy.

Issue Release: 2024

The psychosocial impact of prostate cancer screening for BRCA1 and BRCA2 carriers.

Issue Release: 2024

CDH1 Genotype Exploration in Women With Hereditary Lobular Breast Cancer Phenotype.

Issue Release: 2024

Genomic landscape of comprehensive genomic profiling in patients with malignant solid tumors in Japan.

Issue Release: 2024

Walking the tightrope: Fertility preservation among hereditary breast and ovarian Cancer syndrome Previvors.

Issue Release: 2024

Senaparib as first-line maintenance therapy in advanced ovarian cancer: a randomized phase 3 trial.

Issue Release: 2024

The role of germline BRCA1 & BRCA2 mutations in familial pancreatic cancer: A systematic review and meta-analysis.

Issue Release: 2024

The role of family history in predicting germline pathogenic variant carriers who develop pancreatic cancer: Results of a multicenter collaboration.

Issue Release: 2024

[BRCA mutations and decision regret: a comprehensive analysis of existing research through a scoping review and reflections from a nursing perspective.]

Issue Release: 2024

Outcomes of a universal germline screening program in a community urology practice.

Issue Release: 2024

The Use of Glucagon-like Peptide-1 Receptor Agonists in Patients with Type 2 Diabetes Mellitus Does Not Increase the Risk of Pancreatic Cancer: A U.S.-Based Cohort Study.

Issue Release: 2024

Effects of clinical covariates on serum miRNA expression among women without ovarian cancer.

Issue Release: 2024

Screening in Women With BRCA Mutations Revisited.

Issue Release: 2024

What is the Importance of Data in Epidemiology?

What are the Challenges in Achieving These Objectives?

Why is the Microbiome Important in Epidemiology?

How Does Community Empowerment Impact Disease Prevention?

What are the Sources of Contamination?

What Challenges Exist in Implementing Real-Time Updates?

How Does Duration of Exposure Affect Vulnerable Populations?

How Do Environmental Health Interventions Work?

Why are Publication Sources Important?

What Are the Challenges in Integrating Patient Perspectives?

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